The primary mechanism of action for ED medications like Vilitra involves inhibiting the enzyme PDE5, which regulates blood flow in the penis. By blocking PDE5, these medications promote the relaxation of smooth muscle cells and dilation of blood vessels, resulting in increased blood flow to the penis and the ability to achieve and maintain an erection. While the overall mechanism is similar among these medications, subtle differences in their chemical structures may lead to variations in onset times and durations of action.

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